Business Information Systems, Incorporated is currently headquartered in Paducah, Kentucky.

The corporation's primary data center is located 300 miles to the southeast of Paducah in the Knoxville, Tennessee metropolitan area.

Upon obtaining funding, a feasibility study will be conducted to evaluate if the headquarters will remain in Paducah or be located to a larger metropolitan area such as Nashville, Tennessee or Knoxville, Tennessee. Movement of the company headquarters to a larger area would give the initial sales staff a larger customer base along with easier access. Paducah has a population of 25,661 with an area metropolitan population of 98,127.

The Knoxville area was choosen as the data center because of it's georgaphic location (away from earthquake faultlines and flood plains), skilled labor force, multiple tier 1 communications companies, low cost-of-living, and easy access via the multiple interstates servicing the area (I-40, I-75 and I-81) and a major airport servicing multiple carriers. Knoxville has a population of 681,525 with an area metropolitan population of 1,029,155.